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SCIO press conference on COVID-19 origin tracing

Sci-Tech
On July 22, the State Council Information Office (SCIO) held a press conference in Beijing on COVID-19 origin tracing.

China.org.cnUpdated:  July 25, 2021

CCTV:

As mentioned earlier, tracing the origin of a virus is a long-term complex scientific issue. Relevant origin tracing work was carried out on the 1918 flu pandemic, 2009 H1N1 pandemic, and the global AIDS epidemic. This time, the inquiry into the origin of the COVID-19 has also been carried out globally. What is its significance and the reasons for it? Thank you.

Wang Chen:

Let me answer this question. This is a very important and necessary scientific and health matter. There are three important issues of an infectious disease. The first is the source of infection; the second is the transmission route; and the third is who is likely to be infected, the so-called susceptible groups. These three issues are important scientific links and scientific elements for us to understand the infectious disease. Origin tracing is related to the issues of source and transmission route. Therefore, by clarifying the issue of origins, we can answer the question of where the pathogen of this infectious disease came from. It holds important value not only for this infectious disease, but also has reference significance for the prevention and control of other infectious diseases in the future. The scientific community around the world is deeply interested in this issue, and it is a key matter that we need to focus on and explore. Therefore, this matter is worth exploring. But as Mr. Zeng said just now, we must realize that it is complex, and we need to hold a particularly objective and scientific attitude when probing into origins of a virus. 

Asahi Shimbun:

I have two questions. First, the WHO proposed last week to conduct a second phase of the study into the origin of COVID-19 in China, including an investigation into Wuhan's seafood markets as well as audits of relevant research institutions like the WIV. They expect China to support this process in a spirit of transparency. How do you comment on this? Will China welcome the second phase of the COVID-19 origin probe? Second, in a report released in March on the China Part of the global study of the origins of COVID-19, the WHO said it was extremely unlikely that the virus escaped from a laboratory. However, some scientists have voiced their views in an article published in Science magazine this May, saying that consideration should be given to both a natural spillover and a lab accident. Two countries initially reported the COVID-19 outbreak. Do you think the virus was caused by natural spillover or human factors? Thank you.

Zeng Yixin:

I'll take the first question. Thanks for asking this question. I would like to express my thoughts on the WHO's plan to conduct the second phase of the study into the origin of COVID-19. Honestly speaking, I was rather shocked over the news, because the plan has listed the hypothesis that China's breach of laboratory protocols caused the virus to leak as one of the research priorities. From this point, I can feel that the plan showed disrespect for common sense and arrogance toward science.

First, rumors including one about three WIV staff falling ill and the other one about the WIV conducting so-called "gain of function" experiments on the virus were dispelled long ago. They are pure lies.

Second, RaTG-13, the most similar coronavirus that the WIV collected from bat specimens, shares only 96.2% homology with SARS-CoV-2. 

Moreover, some have wondered if the SARS-CoV-2 is a man-made virus. Some Indian researchers published a preprint scientific manuscript saying that they have found similarities between SARS-CoV-2 and HIV, speculating that the SARS-CoV-2 was man-made. The authors withdrew the paper after being criticized by their international peers. As many other viruses also show similar sequences, we cannot infer simply from this point that the SARS-CoV-2 was man-made. Based on thorough analyses, many experts concluded that there are not any traces of modification in the virus. It's common knowledge to genetic engineers that the artificial modification of a virus will definitely leave traces. But SARS-CoV-2 doesn't have any such traces, which totally rules out the theory that it was man-made.

So far, none of the staff or post-graduate students at the WIV have ever contracted SARS-CoV-2, nor has the WIV conducted any gain-of-function research on coronaviruses. There is no so-called man-made virus there. Then how could it happen that the virus leaked from the laboratory due to violations of lab procedures? Therefore, the "lab leak" theory goes against the common sense and scientific law. More importantly, the WHO sent an expert team on a field trip to the WIV and arrived at the conclusion that a lab leak was extremely unlikely. The experts, selected by the WHO, were authoritative in their respective fields and were rich in research experience. We should respect their conclusions. Therefore, the WHO's plan on the second phase of the study into the COVID-19 origin, as you mentioned, demonstrates a disrespect for common sense and goes against science in some respects. We cannot accept such a plan.

The COVID-19 origin tracing is definitely a scientific issue. The Chinese government has long supported the science-based investigation of the COVID-19 origins, but opposes politicizing the issue. We believe the second phase of origin tracing should be an extension of the first one, guided by the Resolution WHA73.1 and conducted after thorough discussions and negotiations among all WHO members. What was done in the first phase of origin tracing, especially by those that have reached a clear conclusion, should not be repeated. What should be carried out is the origin tracing of early cases, molecular epidemiology, and intermediary hosts in multiple countries and regions based on extensive consultations among WHO members.

The WHO-China joint research, conducted in the first phrase of origin tracing, fully demonstrated that the scientific and rational approach is to conduct work after the WHO and the host country reach consensus on origin-tracing research. The approach not only demonstrates respect to sovereign states, but also promotes origin-tracing work to be conducted in an orderly, smooth, high-quality, and efficient manner. It is necessary to summarize and absorb the successful experience of phase-one work and carry out the next phase based on it. Therefore, on July 4, the Chinese expert team proposed its recommendations on the second-phase origins study to the WHO and exchanged views with WHO experts. In the proposal, we voiced our concerns and core points. We hope the WHO can carefully consider the concerns and advice of Chinese scientists, take investigating the origin of the COVID-19 virus as a scientific issue free from political interference, and proactively and properly conduct sustained investigations into the origin of the virus in multiple countries and regions around the globe. We also call for strengthening international cooperation and exchanges in origin-tracing research, finding the most likely source of the virus as soon as possible and preventing the next pandemic like COVID-19 from happening again by every possible means. Our aim is to better understand the source of SARS-CoV-2, in order to handle the virus effectively and prevent similar pandemics from happening again. Therefore, we must equip ourselves with science-based principles, and promote origin-tracing work in line with scientific rules. This is the attitude adopted by the Chinese government. Thank you. 

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